The prognostic significance of twist in pancreatic cancer and its role in cancer promotion through the regulation of the immune microenvironment and EMT mechanisms
High Twist expression in PAAD signifies a grim prognosis. Its elevated levels not only contribute to tumor progression through EMT induction but also exert regulatory control over the immune microenvironment, leading to immunosuppression and diminished effectiveness of immunotherapy.
Authors
- Yinquan Wang (ORCID: https://orcid.org/0009-0007-4424-4831)
- Renhou Zhi (ORCID: https://orcid.org/0000-0002-8061-842X)
- Qing Li (ORCID: https://orcid.org/0000-0002-3171-4896)
- Yü Liu (ORCID: https://orcid.org/0000-0003-2211-3535)
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
- Shanxi Academy of Medical Sciences (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-10-26
- DOI
- https://doi.org/10.1007/s12672-024-01478-z
- Citations
- 3
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.85