Assessment of myeloid response and iron status among Sudanese pediatric ESKD on hemodialysis through reticulocyte parameters and β-globin mRNA expression
Age and gender significantly influence treatment responses in children with ESKD, highlighting the need to consider growth physiology in anemia management. This study underscores the variability in β-globin mRNA expression and its association with Flow Cytometry parameters, demonstrating their effectiveness in evaluating iron status and guiding rHuEPO dosage.
Authors
- Osama Ali Altayeb
- Nazik Elmalaika Husain (ORCID: https://orcid.org/0000-0001-8333-5735)
- Mugtaba Osman (ORCID: https://orcid.org/0000-0002-5170-6199)
- Abier Abdelaziz Makkawi Abdelrahman
- Nadia Madani Mohammed Ahmed
- Nahla Allam
- Ahmed Ibrahim Marzouk
- Eman Abbas Fadul
Institutions
- Al-Neelain University (SD)
- Omdurman Islamic University (SD)
- Flometrics (United States) (US)
- Alexion Pharma (Switzerland) (CH)
- Hamad Medical Corporation (QA)
- Karary University (SD)
Publication Details
- Journal
- BMC Nephrology
- Published
- 2024-10-26
- DOI
- https://doi.org/10.1186/s12882-024-03806-5
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00