Proteomic analysis of extracellular vesicles derived from canine mammary tumour cell lines identifies protein signatures specific for disease state
EVs from CMT cell lines exhibit distinct protein profiles reflecting malignancy state, allowing us to identify potential biomarkers for canine mammary carcinomas, such as biglycan. Our dataset could therefore potentially serve as a basis for the development of a less invasive clinical diagnostic tool for the characterisation of CMT.
Authors
- Eva‐Maria Packeiser (ORCID: https://orcid.org/0000-0001-6694-3851)
- Matias Aguilera‐Rojas
- Ingo Nölte (ORCID: https://orcid.org/0000-0003-2480-0152)
- Torsten Stein (ORCID: https://orcid.org/0000-0002-9946-1549)
- Kristin Schubert (ORCID: https://orcid.org/0000-0003-4365-084X)
- Isabel Karkossa (ORCID: https://orcid.org/0000-0003-2781-1877)
- Martin von Bergen� (ORCID: https://orcid.org/0000-0003-2732-2977)
- Hugo Murua Escobar (ORCID: https://orcid.org/0000-0001-7123-7986)
- Ralf Einspanier (ORCID: https://orcid.org/0000-0002-9926-9899)
- Gudrun Liebscher
- Tania Gutierrez-Riquelme
Institutions
- Helmholtz Centre for Environmental Research (DE)
- University of Potsdam (DE)
- University of Veterinary Medicine Hannover, Foundation (DE)
- University of Rostock (DE)
- Freie Universität Berlin (DE)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2024-10-26
- DOI
- https://doi.org/10.1186/s12917-024-04331-1
- Citations
- 4
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Freie Universität Berlin