Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma
Collectively, this study revealed the role and mechanism of AREG in negative immune regulation, and targeting AREG might be a novel immunotherapy for LSCC.
Authors
- Ruihua Fang (ORCID: https://orcid.org/0000-0001-5102-7156)
- Yudong Long
- Huanhuan Lyu
- Renqiang Ma
- Lin Chen (ORCID: https://orcid.org/0000-0001-5101-9754)
- Hang Li (ORCID: https://orcid.org/0000-0003-1843-8329)
- Yihui Wen (ORCID: https://orcid.org/0000-0003-4168-5221)
- Rui He (ORCID: https://orcid.org/0000-0001-6242-8705)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Head & Face Medicine
- Published
- 2024-10-26
- DOI
- https://doi.org/10.1186/s13005-024-00466-6
- Citations
- 9
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.54
Funders
- National Natural Science Foundation of China
- Sun Yat-sen University
- Natural Science Foundation of Guangdong Province
- Guangzhou Municipal Science and Technology Project