Rethink Complex Wounds with Biodegradable Temporising Matrix (A Dermal Skin Substitute) - A Retrospective Analysis of Clinical Outcomes in 10 Patients

Background: Complex wounds are common worldwide and necessitate an interdisciplinary, multimodal approach to achieve desirable functional and aesthetic benefits. Microbial colonization, aging population, and rising healthcare costs have all contributed to the economic, social, and clinical costs of complex wound care. This study evaluates effectiveness of biodegradable temporising matrix for treating complex wounds in patients with multiple comorbidities and polymicrobiological colonization. Methods: From March 2023 to December 2023, ten patients received treatment at SMS Hospital, Jaipur, using a biodegradable temporising matrix in patients who had complex wounds. We retrospectively studied the results of these patients. Results: The biodegradable temporizing matrix markedly enhanced wound healing, particularly in patients with various comorbidities and microbiological colonization. This makes it a dependable and promising alternative for reconstruction. Conclusion: It is important to use dermal skin substitutes like the biodegradable temporizing matrix to rebuild the dermal layer and to restore skin functions to normal. It exhibits adequate porosity, regulated biodegradation rates, minimal toxicity and immunogenicity, and retains the integrity of structure during degradation. Our findings suggest that the biodegradable temporising matrix is an effective treatment for complex wounds under challenging circumstances.