Endothelial KLF11 is a novel protector against diabetic atherosclerosis
Our study demonstrates that endothelial KLF11 is an endogenous protective factor against diabetic atherosclerosis. These findings indicate that manipulating KLF11 could be a promising approach for developing novel therapies for diabetes-related cardiovascular complications.
Authors
- Y. Eugene Chen (ORCID: https://orcid.org/0009-0000-8983-739X)
- Guizhen Zhao (ORCID: https://orcid.org/0000-0002-2648-8986)
- Wenying Liang (ORCID: https://orcid.org/0000-0001-9985-6674)
- Minerva T. Garcia-Barrio (ORCID: https://orcid.org/0000-0002-3381-3847)
- Yongjie Deng
- Tianqing Zhu (ORCID: https://orcid.org/0000-0003-3592-5276)
- Haocheng Lu (ORCID: https://orcid.org/0000-0002-5740-8010)
- Yanhong Guo (ORCID: https://orcid.org/0000-0002-3334-9159)
- Yang Zhao (ORCID: https://orcid.org/0000-0002-1362-9823)
- Hongyu Liu (ORCID: https://orcid.org/0000-0002-8111-3941)
- Jifeng Zhang (ORCID: https://orcid.org/0000-0001-5161-4705)
- Lin Chang (ORCID: https://orcid.org/0000-0003-1878-6155)
Institutions
- University of Michigan (US)
- Southern University of Science and Technology (CN)
- Michigan Medicine (US)
- University of Houston (US)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2024-10-26
- DOI
- https://doi.org/10.1186/s12933-024-02473-y
- Citations
- 9
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 2.10
Funders
- American Heart Association
- National Institutes of Health