Safe and successful gut-restricted adsorbent strategy against cirrhosis and acute-on-chronic liver failure

sponsorship: This work was supported by grants from the Scientific Foundation of the Spanish Association Against Cancer (AECC) LABAE20011GARC. Grants from Ministerio de Ciencia Innovacion y Universidades MICINN- Agencia Estatal de Investigacion integrado en el Plan Estatal de Investigacion Cientifica y Tecnica y Innovacion, cofinanciado con Fondos FEDER PID2020-117116RB-I00 MGFB and Proyectos en colaboracion publico- privada 2021 CPP2021-00841. Ramon y Cajal Program contract RYC2018- 024475- 1 from the Spanish Ministry of Science and Innovation. Grants from Fundacion Echebano, Fundacion Mario Losantos and Fundacion M Torres. The Research Foundation Flanders (FWO; Fonds voorWetenschappelijk Onderzoek- Vlaanderen) (G082018N &G025324N) and a clinical mandate to SVDM. Research support KU Leuven (C14/18/087, C14/23/135 & AKUL/19/039). Financial support from the Belgian Association for the Study of the Liver, Gilead Sciences, UZ Leuven (KOOR) and a research grant from the Belgian Week of Gastroenterology(BWGE). (Scientific Foundation of the Spanish Association Against Cancer (AECC)|LABAE20011GARC, Ministerio de Ciencia Innovacion y Universidades MICINN- Agencia Estatal de Investigacion integrado en el Plan Estatal de Investigacion Cientifica y Tecnica y Innovacion, cofinanciado con Fondos FEDER|PID2020-117116RB-I00 MGFB, Proyectos en colaboracion publico- privada 2021|2021 CPP2021-00841, Spanish Ministry of Science and Innovation, Fundacion Echebano, Fundacion Mario Losantos, Fundacion M Torres, Research Foundation Flanders (FWO; Fonds voorWetenschappelijk Onderzoek- Vlaanderen)|G082018N, Research Foundation Flanders (FWO; Fonds voorWetenschappelijk Onderzoek- Vlaanderen)|G025324N, Research support KU|C14/18/087, Research support KU|C14/23/135, Research support KU|AKUL/19/039, Belgian Association for the Study of the Liver, Gilead Sciences, UZ Leuven (KOOR), Belgian Week of Gastroenterology(BWGE))