IMPACT OF FOUR FAT-RICH INFANT FLOURS ON LIPID AND ATHEROGENIC PROFILE OF WISTAR RATS

Dietary fat content influences serum lipid parameters and the incidence of cardiovascular and coronary heart disease. The point of this study was to find out what happened to Wistar rats serum lipid profiles and atherogenic indices when they ate a high-fat PASLoc meal after they had been on a restricted diet. Forty-two male rats, 80 ± 5 days of age, were subjected to 19 days of food restriction and then fed PASLoc infant formula for 14 days. Blood samples from the rats were taken at the end of the periods of not eating and eating so that serum lipid constants (total cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides) could be found and predictive parameters for atherosclerotic and coronary heart disease could be calculated. The results showed that dietary restriction led to an imbalance in serum parameters, with LDL cholesterol (0.11 ±0.01), HDL cholesterol (0.35 ±0.08), total cholesterol (0.60 ±0.07), and triglycerides (0.44 ±0.08) all decreasing. At the end of the dietary experiment, these constants improved according to the standards recommended for rats. Consumption of PASLoc flours had no negative effect on the Castelli indices (CRI-I and CRI-II), the atherogenic coefficient (CA), or the atherogenic plasma index (AIP). The fats contained in these flours do not represent an atherogenic health risk for children.