Prognostic relevance of sarcopenia and tumor‐infiltrating <scp>CD8</scp><sup>+</sup> T cells in patients with hepatocellular carcinoma
Sarcopenia and low CD8 levels are strong independent poor prognostic factors in patients with HCC. Furthermore, sarcopenia patients with high CD8 levels had favorable survival and activated local immunity, suggesting that tumor-infiltrating CD8<sup>+</sup> T cells may play a functionally important role in sarcopenia patients.
Authors
- Masayuki Sho
- Satoshi Yasuda (ORCID: https://orcid.org/0000-0003-4323-7422)
- Kota Nakamura (ORCID: https://orcid.org/0000-0001-6256-4117)
- Minako Nagai (ORCID: https://orcid.org/0000-0003-2102-1276)
- Taichi Terai
- Yuichiro Kohara (ORCID: https://orcid.org/0000-0002-0268-2450)
- Takeshi Sakata (ORCID: https://orcid.org/0009-0006-1406-6280)
- Mariko Miyashita
- Yasuko Matsuo
- Shunsuke Doi
Institutions
- Nara Medical University (JP)
Publication Details
- Journal
- Annals of Gastroenterological Surgery
- Published
- 2024-10-26
- DOI
- https://doi.org/10.1002/ags3.12875
- Citations
- 3
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.98