Interactions between the human milk oligosaccharide 2′-fucosyllactose and Bifidobacterium longum subspecies infantis in influencing systemic immune development and function in piglets
2'-FL stimulates a balanced cytokine profile in healthy piglets without changing immune cell populations. When immune cells are stimulated <i>ex vivo</i> with LPS, 2'-FL primes T-cells for a proinflammatory response, which is moderated by co-administration of Bi-26™.
Authors
- Victoria Daniels
- Ryan N. Dilger (ORCID: https://orcid.org/0000-0003-2538-2845)
- Markus J. Lehtinen (ORCID: https://orcid.org/0000-0002-8091-400X)
- Sharon M. Donovan (ORCID: https://orcid.org/0000-0002-9785-4189)
- Henrik Max Jensen
- Marcia H. Monaco (ORCID: https://orcid.org/0000-0003-1677-7773)
- Arthur C. Ouwehand (ORCID: https://orcid.org/0000-0001-8348-0633)
- Johanna Hirvonen (ORCID: https://orcid.org/0000-0003-0580-9020)
- Niels Juel Christensen (ORCID: https://orcid.org/0000-0002-2291-7886)
- Ratna Mukerjea
Institutions
- University of Illinois Urbana-Champaign (US)
- Ian's Friends Foundation (US)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-10-25
- DOI
- https://doi.org/10.3389/fnut.2024.1444594
- Citations
- 3
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.93
Funders
- DuPont