Association of diuretics with falls and wrist fractures: a Mendelian randomization study
Our findings suggest that the use of loop diuretics (LDs) or potassium-sparing diuretics (PSDs) increases the incidence of falls, but there is no causal relationship between thiazide diuretics (TDs) and falls, and TDs may actually reduce the risk of wrist fractures. Clinical use of diuretics necessitates vigilance and appropriate preventive measures to minimize fall-related events.
Authors
- Jian S. Dai (ORCID: https://orcid.org/0000-0002-9729-1662)
- C Wang (ORCID: https://orcid.org/0000-0002-0243-5409)
- Yongzhong Cheng (ORCID: https://orcid.org/0000-0003-2733-2622)
- Xiaomin Deng (ORCID: https://orcid.org/0000-0002-8466-0211)
- Runmin Cao (ORCID: https://orcid.org/0000-0002-8173-2961)
- Fei Liu (ORCID: https://orcid.org/0000-0002-7848-5226)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Wangjing Hospital of China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2024-10-25
- DOI
- https://doi.org/10.3389/fpubh.2024.1381486
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Academy of Chinese Medical Sciences