The Onset of Systemic Lupus Erythematosus Triggers Nucleus Pulposus Cell Pyroptosis to Exacerbate Intervertebral Disc Degeneration
Our findings highlight the mechanistic link between SLE and IVD degeneration, suggesting potential therapeutic targets for mitigating back pain in SLE patients.
Authors
- Helou Zhang (ORCID: https://orcid.org/0000-0002-6891-1981)
- Zhaobai Lao
- Hongting Jin
- Hongfeng Ruan (ORCID: https://orcid.org/0000-0001-8868-9313)
- Taotao Xu (ORCID: https://orcid.org/0000-0002-2697-1484)
- Fangda Fu
- Changfeng Hu (ORCID: https://orcid.org/0000-0002-1666-6865)
- Yishan Bian (ORCID: https://orcid.org/0000-0002-3938-1758)
- Xin Chen
- Ronghua Bao
- Yuliang Zhang (ORCID: https://orcid.org/0000-0001-7205-7768)
- Chengliang Wu (ORCID: https://orcid.org/0000-0002-1741-8345)
- Shuchao Shen
- X. Fang
- Chengcong Zhou
Institutions
- Zhejiang Chinese Medical University (CN)
- Fuyang City People's Hospital (CN)
- Zhejiang Provincial Hospital of TCM (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/jir.s486297
- Citations
- 4
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- National Natural Science Foundation of China
- Zhejiang Chinese Medical University
- Natural Science Foundation of Zhejiang Province