Characterisation of the tumour microenvironment in primary and recurrent glioblastomas
Early recurrent glioblastomas showed enrichment for TAMs, expressing both pro- and anti-inflammatory markers and B-lymphocytes. This may indicate a time-dependent response to immunotherapy explained by time-dependent alterations in the immune-microenvironment in recurrent glioblastomas.
Authors
- Vilde Pedersen (ORCID: https://orcid.org/0000-0001-7544-7286)
- Eric Hansen (ORCID: https://orcid.org/0000-0003-2829-1316)
- Bjarne Winther Kristensen (ORCID: https://orcid.org/0000-0002-6352-0826)
- Jesper Dupont Ewald (ORCID: https://orcid.org/0000-0002-3452-2291)
- Martin Haupt‐Jorgensen (ORCID: https://orcid.org/0000-0003-4088-5862)
- Arnon Møldrup Knudsen (ORCID: https://orcid.org/0000-0003-0191-1714)
Institutions
- University of Copenhagen (DK)
- University of Southern Denmark (DK)
- Odense University Hospital (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Zealand University Hospital (DK)
Publication Details
- Journal
- Neuropathology and Applied Neurobiology
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1111/nan.13012
- Citations
- 8
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.50
Funders
- Kræftens Bekæmpelse
- Odense Universitetshospital
- Syddansk Universitet