Risk factors associated with multidrug-resistant Klebsiella pneumoniae infections: a multicenter observational study in Lebanese hospitals
MDR K. pneumoniae infections are steadily rising in Lebanon, along with an increase in ESBL-producing and CRKP cases. The main risk factors for MDR K. pneumoniae infections were male sex, recent antibiotic use, and cancer chemotherapy. ESBL-producing infections were associated with advanced age, higher CCI, and recent antibiotic use, while CRKP infections were linked to male sex, prior antibiotic use, and prolonged hospital stays. This situation is further exacerbated by inadequate healthcare infrastructure and suboptimal national surveillance. Strengthening local surveillance and implementing effective antibiotic stewardship programs are critical to managing this growing threat..
Authors
- Patricia Shuhaiber (ORCID: https://orcid.org/0000-0003-2072-9248)
- Abdalla El-Lakany
- Carole Dib
- Tareq Lewis Mukattash (ORCID: https://orcid.org/0000-0003-0200-9845)
- Hani M. J. Khojah (ORCID: https://orcid.org/0000-0002-0586-1526)
- Mariam Hassan (ORCID: https://orcid.org/0000-0002-7972-9827)
- Rania Itani (ORCID: https://orcid.org/0000-0003-4316-3224)
- Hamza Raychouni (ORCID: https://orcid.org/0009-0006-2856-8740)
- Rahaf Kibrit
Institutions
- Jordan University of Science and Technology (JO)
- University of Balamand (LB)
- Taibah University (SA)
- Beirut Arab University (LB)
- Arab Open University (LB)
- American University of Beirut Medical Center (LB)
- Lebanese Hospital Geitaoui-University Medical Center (LB)
- Makassed General Hospital (LB)
- Alexandria University (EG)
Publication Details
- Journal
- BMC Public Health
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1186/s12889-024-20474-0
- Citations
- 15
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 2.55