Potential Mechanisms of COVID-19 Related Nervous System Damage and Effects on Female Fertility

Signs and symptoms that persist or worsen beyond the "acute COVID-19" stage are referred to as long-COVID. These patients are more likely to suffer from multiple organ failure, readmission, and mortality. According to a recent theory, long-lasting COVID-19 symptoms may be caused by abnormal autonomic nervous system (ANS) activity, such as hypovolemia, brain stem involvement, and autoimmune reactions. Furthermore, COVID-19 can also cause impaired fertility in women, which may also be related to inflammation and immune responses. Currently, few treatments are available for long-COVID symptoms. This article reviews the major effects of COVID-19 on the nervous system and female fertility, as well as offers potential treatment approaches.

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Publication Details

Journal
Current Medicinal Chemistry
Published
2024-10-25
DOI
https://doi.org/10.2174/0109298673333968241011092801
Primary Topic
COVID-19 Impact on Reproduction
Type
article
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article

Potential Mechanisms of COVID-19 Related Nervous System Damage and Effects on Female Fertility

Shenshen Hu, Huadong Liu, Chenyue Qian, Jingjin Liu
Current Medicinal Chemistry
COVID-19 Impact on Reproduction
article

Potential Mechanisms of COVID-19 Related Nervous System Damage and Effects on Female Fertility

Shenshen Hu, Huadong Liu, Chenyue Qian, Jingjin Liu
article en

Abstract

Signs and symptoms that persist or worsen beyond the "acute COVID-19" stage are referred to as long-COVID. These patients are more likely to suffer from multiple organ failure, readmission, and mortality. According to a recent theory, long-lasting COVID-19 symptoms may be caused by abnormal autonomic nervous system (ANS) activity, such as hypovolemia, brain stem involvement, and autoimmune reactions. Furthermore, COVID-19 can also cause impaired fertility in women, which may also be related to inflammation and immune responses. Currently, few treatments are available for long-COVID symptoms. This article reviews the major effects of COVID-19 on the nervous system and female fertility, as well as offers potential treatment approaches.

Current Medicinal ChemistryVol. 32(42)
Harbin Medical University (CN), Jinan University (CN), Southern University of Science and Technology (CN), Second Affiliated Hospital of Harbin Medical University (CN), Southern Medical University Shenzhen Hospital (CN), Shenzhen Second People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 70%
COVID-19 Impact on Reproduction
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