In silico Study of Novel Tryptanthrin-Based Topoisomerase Inhibitors

Our computational approach was successful in identifying ligands that are potentially potent topoisomerase inhibitors. These can be tested further using <i>in vitro</i> and <i>in vivo</i> analysis.

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Publication Details

Journal
Medicinal Chemistry
Published
2024-10-25
DOI
https://doi.org/10.2174/0115734064334604241014024205
Primary Topic
Cancer therapeutics and mechanisms
Type
article
Field-Weighted Citation Impact
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article

In silico Study of Novel Tryptanthrin-Based Topoisomerase Inhibitors

Mukesh Kumar Kumawat, Kapil Kumar
Medicinal Chemistry
Cancer therapeutics and mechanisms
article

In silico Study of Novel Tryptanthrin-Based Topoisomerase Inhibitors

Mukesh Kumar Kumawat, Kapil Kumar
article en

Abstract

Our computational approach was successful in identifying ligands that are potentially potent topoisomerase inhibitors. These can be tested further using <i>in vitro</i> and <i>in vivo</i> analysis.

Medicinal ChemistryVol. 21(6)
Apeejay Stya University (IN), University of Petroleum and Energy Studies (IN), Dehradun Institute of Technology University (IN)
Good health and well-being
Openalex Percentile: Top 83%
Cancer therapeutics and mechanisms
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