Design, Synthesis, Molecular Docking, Pharmacokinetic Properties, and Molecular Dynamics Simulation of Sulfonyl Derivatives of Benzimidazole against Parkinson’s Disease
This study indicates that the binding affinity of most of the hits was superior to that of known MAO inhibitors; therefore, these newly synthesized benzimidazole derivatives may be developed into essential drug candidates for the treatment of PD.
Authors
- Santanu Basak (ORCID: https://orcid.org/0000-0002-1098-394X)
- Bimal Debnath (ORCID: https://orcid.org/0000-0002-9755-9518)
- Himesh Barman
- Kaushik Sarkar (ORCID: https://orcid.org/0000-0002-3782-0948)
- Prithwiraj Dey (ORCID: https://orcid.org/0000-0001-5373-1876)
- Subarna Roy (ORCID: https://orcid.org/0000-0002-6594-8615)
- Bhagat Singh (ORCID: https://orcid.org/0000-0003-2332-9581)
- Shongkour Roy (ORCID: https://orcid.org/0000-0001-7114-7630)
- Subhadeep Sen (ORCID: https://orcid.org/0000-0002-8650-6234)
- Goutam Biswas (ORCID: https://orcid.org/0000-0002-1488-2003)
- Rajesh Kumar Das (ORCID: https://orcid.org/0009-0008-8036-9583)
Institutions
- University of North Carolina at Greensboro (US)
- Cooch Behar Panchanan Barma University (IN)
- North Bengal University (IN)
- Indian Institute of Technology Indore (IN)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2024-10-25
- DOI
- https://doi.org/10.2174/0109298673337912241007120510
- Citations
- 3
- Primary Topic
- Electrochemical sensors and biosensors
- Type
- article
- Field-Weighted Citation Impact
- 0.63