Corticotropin-Releasing Factor Modulates Binge-Like Ethanol Drinking in a Sex-Dependent Manner: Impact of Amygdala Deletion and Inhibition of a Central Amygdala to Lateral Hypothalamus Circuit
These observations provide novel evidence that CRF+ CeA to LH neurocircuitry is more sensitive for modulating binge-like ethanol intake in male mice, which may provide insight into the mechanisms that guide known sex differences in binge-like ethanol intake.
Authors
- Sophia Lee (ORCID: https://orcid.org/0000-0001-6002-8708)
- Todd E. Thiele (ORCID: https://orcid.org/0000-0001-8908-9256)
- Sofia Neira (ORCID: https://orcid.org/0000-0003-3639-2897)
- Francisca Carvajal (ORCID: https://orcid.org/0000-0002-4507-2863)
- Sophie C. Bendrath (ORCID: https://orcid.org/0000-0002-4423-6598)
- Montserrat Navarro (ORCID: https://orcid.org/0000-0002-6249-7425)
- José Manuel Lerma-Cabrera (ORCID: https://orcid.org/0000-0001-6986-5510)
- Ana Paula Segantine Dornellas (ORCID: https://orcid.org/0000-0001-8342-7402)
- Thomas L. Kash (ORCID: https://orcid.org/0000-0002-4747-4495)
- Harold L. Haun (ORCID: https://orcid.org/0000-0002-4781-3733)
- Eric J. Delpire (ORCID: https://orcid.org/0000-0002-3702-1599)
- Anne M. Dankert (ORCID: https://orcid.org/0000-0002-3046-504X)
- Hernán G. Méndez
Institutions
- University of North Carolina at Chapel Hill (US)
- University of Almería (ES)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Biological Psychiatry Global Open Science
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1016/j.bpsgos.2024.100405
- Citations
- 12
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- Howard Hughes Medical Institute
- National Institutes of Health
- National Institute on Alcohol Abuse and Alcoholism
- National Institute on Drug Abuse