Association of MRI findings with intra-articular tumour extension
MRI provides excellent discrimination for determining intra-articular tumour extension when multiple direct signs of invasion are present. When MRI results are equivocal, assessment of synovial thickening increases MRI's discriminatory ability to predict intra-articular joint extension. These results should be interpreted in the context of the study's limitations. The inclusion of only extra-articular excisions enriched the sample for true positive cases. Direct signs likely varied with tumour histology and location. A larger, prospective study of periarticular bone sarcomas with spatial correlation of histological and radiological findings is needed to validate these results before their adoption in clinical practice.
Authors
- Anton S. Becker (ORCID: https://orcid.org/0000-0001-8372-6496)
- Sinchun Hwang (ORCID: https://orcid.org/0000-0002-6402-3020)
- Max Vaynrub (ORCID: https://orcid.org/0000-0001-7364-3259)
- Lorenzo Deveza (ORCID: https://orcid.org/0000-0001-7137-573X)
- M Amine
- Meera Hameed (ORCID: https://orcid.org/0000-0002-2766-243X)
- John Nolan
Institutions
- Memorial Sloan Kettering Cancer Center (US)
Publication Details
- Journal
- Bone & Joint Open
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1302/2633-1462.510.bjo-2024-0047.r2
- Citations
- 1
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- Memorial Sloan-Kettering Cancer Center
- National Institutes of Health
- National Cancer Institute