Preparation of Ibuprofen-Loaded Inhalable γCD-MOFs by Freeze-Drying Using the QbD Approach

This research successfully demonstrates the innovative use of freeze-drying to produce γCD-MOFs for inhalable IBU delivery. The method enabled to modify the particle size, which was crucial for successful pulmonary intake, emphasizing the need for further investigation of these formulations as effective delivery systems.

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Publication Details

Journal
Pharmaceutics
Published
2024-10-24
DOI
https://doi.org/10.3390/pharmaceutics16111361
Citations
7
Primary Topic
Gas Sensing Nanomaterials and Sensors
Type
article
Field-Weighted Citation Impact
1.46
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article

Preparation of Ibuprofen-Loaded Inhalable γCD-MOFs by Freeze-Drying Using the QbD Approach

Rita Ambrus, Ildikó Csóka, Petra Party, Milena Sorrenti et al.
7 citations
Pharmaceutics
Gas Sensing Nanomaterials and Sensors
1.46
article

Preparation of Ibuprofen-Loaded Inhalable γCD-MOFs by Freeze-Drying Using the QbD Approach

Rita Ambrus, Ildikó Csóka, Petra Party, Milena Sorrenti, Anett Motzwickler-Németh, P Simon
article en
7 citations

Abstract

This research successfully demonstrates the innovative use of freeze-drying to produce γCD-MOFs for inhalable IBU delivery. The method enabled to modify the particle size, which was crucial for successful pulmonary intake, emphasizing the need for further investigation of these formulations as effective delivery systems.

PharmaceuticsVol. 16(11)
University of Szeged (HU), University of Pavia (IT)
Openalex Percentile: Top 17%
Gas Sensing Nanomaterials and Sensors
1.46
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