Evaluation of oxidative stress biomarkers for differentiating bacterial and viral infections: a comparative study of glutathione disulfide (GSSG) and reduced glutathione (GSH)

These findings suggest that the GSH/GSSG ratio could be used as a biomarker in distinguishing between bacterial and viral infections, offering potential clinical applications for more accurate diagnosis. Further research is required to validate these results in larger cohorts and to explore the underlying mechanisms of oxidative stress in pathogen-specific immune responses.

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Publication Details

Journal
Medicine and Pharmacy Reports
Published
2024-10-24
DOI
https://doi.org/10.15386/mpr-2821
Citations
6
Primary Topic
Sulfur Compounds in Biology
Type
article
Field-Weighted Citation Impact
1.77
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article

Evaluation of oxidative stress biomarkers for differentiating bacterial and viral infections: a comparative study of glutathione disulfide (GSSG) and reduced glutathione (GSH)

Oana Zănoagă, Laura Pop, Paul Chiroi, Elena Ioana Braicu et al.
6 citations
Medicine and Pharmacy Reports
Sulfur Compounds in Biology
1.77
article

Evaluation of oxidative stress biomarkers for differentiating bacterial and viral infections: a comparative study of glutathione disulfide (GSSG) and reduced glutathione (GSH)

Oana Zănoagă, Laura Pop, Paul Chiroi, Elena Ioana Braicu, Antonia Haranguș, Ioana Rada Popa Ilie, Cristina Cismaru, Zaki Milhelm, Andrada Iovita
article en
6 citations

Abstract

These findings suggest that the GSH/GSSG ratio could be used as a biomarker in distinguishing between bacterial and viral infections, offering potential clinical applications for more accurate diagnosis. Further research is required to validate these results in larger cohorts and to explore the underlying mechanisms of oxidative stress in pathogen-specific immune responses.

Medicine and Pharmacy ReportsVol. 98(1)
Iuliu Hațieganu University of Medicine and Pharmacy (RO), Clinical Emergency Hospital Bucharest (RO), Clinica de Pneumologie Iaşi (RO), County Hospital (GB)
Openalex Percentile: Top 16%
Sulfur Compounds in Biology
1.77
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Evaluation of oxidative stress biomarkers for differentiating bacterial and viral infections: a comparative study of glutathione disulfide (GSSG) and reduced glutathione (GSH) — Oana Zănoagă, Laura Pop, et al. · Medicine and Pharmacy Reports (2024) | TGRS Research Map | TGRS