Discussion on: ‘Simple or complex statistical models: Non-traditional regression models with intuitive interpretations’ by Gillian Z. Heller

1 Comment by Jan Beyersmann My comment focuses on the time-to-event part of Professor Heller's paper but will also lean on the binary outcome part for discussion of the proposed concept of 'simplicity'. For survival data, key points made by Professor Heller include (in my words): 1. Hazards are not easy to interpret. 2. Parametric models are underused. 3. Accelerated failure time (AFT) modelling (and, perhaps, generalizations of it) provides an attractive interpretation for survival times T ∈ (0, ∞). I contend that there is general agreement on these points in survival analysis, although it does not necessarily translate into statistical practice. Hence, reading Professor Heller's fresh take on the subject, rightfully putting a spotlight on the advances made in distributional regression, was a pleasure. The aim of my comment is to argue that not one approach solves it all and why hazards have been and arguably will continue to be central to time-to-event analyses: they are the identifiable quantities and work in very general event history scenarios beyond the T ∈ (0, ∞) situation subject to (random) right-censoring.

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Publication Details

Journal
Statistical Modelling
Published
2024-10-25
DOI
https://doi.org/10.1177/1471082x241277642
Primary Topic
Statistical Methods and Inference
Type
article
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article

Discussion on: ‘Simple or complex statistical models: Non-traditional regression models with intuitive interpretations’ by Gillian Z. Heller

Thomas Kneib, Guadalupe Gómez Melis, Vito M. R. Muggeo, Gillian Z. Heller et al.
Statistical Modelling
Statistical Methods and Inference
article

Discussion on: ‘Simple or complex statistical models: Non-traditional regression models with intuitive interpretations’ by Gillian Z. Heller

Thomas Kneib, Guadalupe Gómez Melis, Vito M. R. Muggeo, Gillian Z. Heller, Geert Molenberghs, Stijn Vansteelandt, Jan Beyersmann
article en

Abstract

1 Comment by Jan Beyersmann My comment focuses on the time-to-event part of Professor Heller's paper but will also lean on the binary outcome part for discussion of the proposed concept of 'simplicity'. For survival data, key points made by Professor Heller include (in my words): 1. Hazards are not easy to interpret. 2. Parametric models are underused. 3. Accelerated failure time (AFT) modelling (and, perhaps, generalizations of it) provides an attractive interpretation for survival times T ∈ (0, ∞). I contend that there is general agreement on these points in survival analysis, although it does not necessarily translate into statistical practice. Hence, reading Professor Heller's fresh take on the subject, rightfully putting a spotlight on the advances made in distributional regression, was a pleasure. The aim of my comment is to argue that not one approach solves it all and why hazards have been and arguably will continue to be central to time-to-event analyses: they are the identifiable quantities and work in very general event history scenarios beyond the T ∈ (0, ∞) situation subject to (random) right-censoring.

Statistical ModellingVol. 24(6)
The University of Sydney (AU), Ghent University (BE), National Health and Medical Research Council (AU), University of Göttingen (DE), Hasselt University (BE), University of Palermo (IT), Universitat Politècnica de Catalunya (ES), KU Leuven (BE)
Reduced inequalities
Openalex Percentile: Top 81%
Statistical Methods and Inference
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