Treatment of lung adenocarcinoma with chemotherapy helps mitigate chronic myeloid leukaemia progression: A case report

Treatment outcomes for inoperable advanced non-small cell lung cancer have improved in recent years. However, information on coexisting haematological tumours is lacking. The present patient was a 65-year-old woman with stage IVA lung adenocarcinoma. The patient was administered a combination of platinum therapy and immune checkpoint inhibitors. The patient was subsequently diagnosed with chronic myeloid leukaemia (CML) following leukocytosis. Carboplatin and pemetrexed combination therapy resulted in shrinkage of lung cancer. Improvements in peripheral blood leukocyte counts and bone marrow findings were observed. These results suggested that the treatment of lung cancer may control the course of CML.

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Publication Details

Journal
Oncology Letters
Published
2024-10-25
DOI
https://doi.org/10.3892/ol.2024.14777
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
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Treatment of lung adenocarcinoma with chemotherapy helps mitigate chronic myeloid leukaemia progression: A case report

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Treatment of lung adenocarcinoma with chemotherapy helps mitigate chronic myeloid leukaemia progression: A case report

Ryotaro Kida, Masayo Yamamoto, Ryohei Yoshida, Mishie Ann Tanino, Hiraku Yanada, Takuya Funayama, Yasuhiro Umekage, Kazunori Nagasue, Kiichi Nitanai, Ryota Shigaki, Takaaki Sasaki, Yoshinori Minami, Akari Yagita, Chie Mori
article en

Abstract

Treatment outcomes for inoperable advanced non-small cell lung cancer have improved in recent years. However, information on coexisting haematological tumours is lacking. The present patient was a 65-year-old woman with stage IVA lung adenocarcinoma. The patient was administered a combination of platinum therapy and immune checkpoint inhibitors. The patient was subsequently diagnosed with chronic myeloid leukaemia (CML) following leukocytosis. Carboplatin and pemetrexed combination therapy resulted in shrinkage of lung cancer. Improvements in peripheral blood leukocyte counts and bone marrow findings were observed. These results suggested that the treatment of lung cancer may control the course of CML.

Oncology LettersVol. 29(1)
Asahikawa Medical University (JP)
Good health and well-being
Openalex Percentile: Top 69%
Acute Myeloid Leukemia Research
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