A new <i>cis</i>‐clerodane‐type furanoditerpenoid from the leaves of <i>Tinospora crispa</i> with inhibitory effect on LPS induced NO production in RAW 264.7 cells
Abstract Three cis ‐clerodane‐type furanoditerpenoids ( 1 ‐ 3 ) including one new compound named tinocrioside D ( 1 ) together with four known compounds ( 4 ‐ 7 ) were isolated from the leaves of Tinospora crispa . Their chemical structures were determined based on the 1D, 2D‐NMR, HR‐ESI‐MS, and ECD data analyses in comparison with the reported data. Compounds 1 – 3 showed weak inhibition of LPS‐induced NO production in mouse mononuclear macrophages.
Authors
- Phan Văn Kiệm (ORCID: https://orcid.org/0000-0003-0756-6990)
- Bùi Hữu Tài (ORCID: https://orcid.org/0000-0002-2034-3786)
- Lê Đức Giang (ORCID: https://orcid.org/0000-0002-3269-9915)
- Nguyễn Văn Quốc (ORCID: https://orcid.org/0000-0002-3551-6547)
- Vu Kim Thu
- Phạm Hải Yến
- Đan Thị Thúy Hằng
Institutions
- Vinh University (VN)
- Hanoi University of Mining and Geology (VN)
- Vietnam Academy of Science and Technology (VN)
Publication Details
- Journal
- Vietnam Journal of Chemistry
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1002/vjch.202400226
- Primary Topic
- Phytochemicals and Medicinal Plants
- Type
- article
- Field-Weighted Citation Impact
- 0.00