Potential mechanisms of metabolic reprogramming induced by ischemia–reperfusion injury in diabetic myocardium
Metabolic reprogramming of diabetic myocardial I/RI may be the main cause of increased myocardial vulnerability. The number of myocardial subtype Cluster 0 increased significantly, and PPARA PPARA is a ligand-activated receptor of the nuclear hormone receptor family that plays a central regulatory role in lipid metabolism. signaling pathway activation may be a potential mechanism for reprogramming metabolism in diabetic myocardium.
Authors
- Yuneldi Anwar
- Zheng Yan (ORCID: https://orcid.org/0000-0001-8966-6295)
- Haochuan Ma (ORCID: https://orcid.org/0000-0002-7663-120X)
- Yuxuan He (ORCID: https://orcid.org/0009-0002-3005-3421)
- Jiyao Zhao
- Jiang Wang
- Junjie Wang (ORCID: https://orcid.org/0009-0001-9328-5863)
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Journal of Diabetes
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1111/1753-0407.70018
- Citations
- 2
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Xinjiang Medical University