Human adipose-derived stem cells promote migration of papillary thyroid cancer cell via leptin pathway
ADSCs upregulate MMP-2 levels of thyroid cancer cells through exocrine leptin, thereby promoting cancer cell migration, which may be one of the key mechanisms by which obesity increases the invasiveness of thyroid cancer.
Authors
- Rui Jiang (ORCID: https://orcid.org/0000-0003-1849-3643)
- Qi-Lan Jiang (ORCID: https://orcid.org/0009-0006-9981-2050)
- Ying Li (ORCID: https://orcid.org/0000-0002-3506-1255)
- Bo‐Tao Zhang (ORCID: https://orcid.org/0000-0003-0299-8575)
- Jun Jiang (ORCID: https://orcid.org/0000-0003-1292-7236)
- Yang Zeng (ORCID: https://orcid.org/0009-0000-4133-4080)
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1080/07853890.2024.2419990
- Citations
- 6
- Primary Topic
- Biomarkers in Disease Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.44
Funders
- National Natural Science Foundation of China