Bis(aminoalkyl)cyclopropenylidene (BAC)-Catalyzed Intramolecular Annulation of 2-(2-Formylaryl)-aryl-Substituted <i>p</i>-Quinone Methides to 9-Phenanthrol Derivatives
This article describes a bis(aminoalkyl)cyclopropenylidene (BAC)-catalyzed intramolecular annulation of strategically designed 2-(2-formylaryl)-phenyl-substituted <i>p</i>-quinone methides (<i>p-</i>QMs) to access 9-phenanthrol derivatives and related carbocycles. In addition, the synthetic utility of this methodology has been demonstrated in the synthesis of the seven-membered carbocyclic core of resveratrol-based natural products (±)-shoreaphenol and (±)-malibatol A.
Authors
- Ramasamy Vijaya Anand (ORCID: https://orcid.org/0000-0001-9490-4569)
- Deepak Baranwal (ORCID: https://orcid.org/0000-0001-5094-3179)
- Pavit K. Ranga
- Arun Kumar (ORCID: https://orcid.org/0000-0002-8036-8766)
- Feroz Ahmad
- Shaheen Fatma
Institutions
- Indian Institute of Science Education and Research Mohali (IN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1021/acs.joc.4c01993
- Citations
- 7
- Primary Topic
- Synthesis of Indole Derivatives
- Type
- article
- Field-Weighted Citation Impact
- 1.75
Funders
- Ministry of Education, India
- Indian Institute of Science Education and Research Mohali