Exploring Potential Biomarkers and Molecular Mechanisms of Cutaneous Squamous Cell Carcinoma Based on Bioinformatics
In conclusion, we have identified CCNA2, CCNB2, and UBE2C as novel biomarkers for cSCC, and the NEAT1/H19-hsa-miR-148a-3p-CCNA2 and NEAT1-hsa-miR-140-3p-UBE2C ceRNA networks may represent molecular mechanisms under-lying cSCC progression. The findings of this study offer new diagnostic and therapeutic options for cSCC patients.
Authors
- Jia Bai (ORCID: https://orcid.org/0009-0003-0398-9109)
- Chengxin Li (ORCID: https://orcid.org/0000-0003-1765-9605)
- Zhu Wen-Wei
- Qingqing Guo (ORCID: https://orcid.org/0000-0003-2863-805X)
- Xiaoqiang Liang
- Fang Xie (ORCID: https://orcid.org/0000-0003-2528-5041)
- Jiayue Qi (ORCID: https://orcid.org/0000-0002-3645-4296)
Institutions
- Nankai University (CN)
- Chinese PLA General Hospital (CN)
Publication Details
- Journal
- OncoTargets and Therapy
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/ott.s468399
- Citations
- 1
- Primary Topic
- Melanoma and MAPK Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- National Science Foundation
- National Natural Science Foundation of China