Investigating Marumoside A as a Bone Sarcoma Anticancer Agent using Computational Insights
Bone sarcoma, a group of aggressive cancers arising from bone or soft tissues, remains challenging to treat effectively. This study investigates the potential of Marumoside A, a phytochemical, as a therapeutic agent against bone sarcoma using computational methods. Molecular docking was performed to explore the interactions between Marumoside A and key protein targets involved in bone sarcoma progression. Binding affinities and interaction profiles were analyzed to identify its mechanism of action. Drug-likeness and ADMET properties were assessed using SwissADME and StopTox tools, confirming compliance with pharmacokinetic and safety requirements. Marsumoside A exhibited strong binding affinities, favorable pharmacokinetic properties, and a low toxicity profile, highlighting its promise as a candidate for further preclinical evaluation. These findings underscore the therapeutic potential of Marumoside A in bone sarcoma treatment and warrant experimental validation.
Institutions
- Alagappa University (IN)
Publication Details
- Journal
- Shanlax International Journal of Arts Science and Humanities
- Published
- 2024-10-25
- DOI
- https://doi.org/10.34293/sijash.v12i1.8019
- Primary Topic
- Potato Plant Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00