The causal relationship between immune cell-mediated gut microbiota and ulcerative colitis: a bidirectional two-sample, mediation Mendelian randomization analysis
There is a clear causal relationship between certain gut microbiota and UC, and CD11b on Mo MDSC is a significant mediator between <i>B. bifidum</i> and UC, providing new insights for the clinical treatment of UC.
Authors
- Jinyin Xiao
- Xiajun Guo (ORCID: https://orcid.org/0009-0003-7933-0976)
- Zhenquan Wang (ORCID: https://orcid.org/0000-0002-7924-060X)
- Youwei Lin (ORCID: https://orcid.org/0000-0001-7561-5577)
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
- Xiangshan County First People's Hospital (CN)
- Xiang Yang No.1 People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-10-25
- DOI
- https://doi.org/10.3389/fnut.2024.1433545
- Citations
- 2
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province