HIV replication and tuberculosis risk among people living with HIV in Europe: A multicohort analysis, 1983–2015
Our results indicate that ongoing HIV replication (suboptimal HIV control) is an important risk factor for TB, independent of CD4 count. Those at highest risk of TB are people from TB-endemic countries. Close monitoring and TB preventive therapy for people with suboptimal HIV control is important.
Authors
- PETER C. REISS (ORCID: https://orcid.org/0000-0001-7896-6428)
- Nicolas Banholzer (ORCID: https://orcid.org/0000-0003-0138-6120)
- Vincent Le Moing (ORCID: https://orcid.org/0000-0002-9529-2792)
- Ole Kirk (ORCID: https://orcid.org/0000-0003-1995-1837)
- David Kraus (ORCID: https://orcid.org/0000-0003-4376-3932)
- Dominique Salmon (ORCID: https://orcid.org/0000-0003-1229-2429)
- Andrew Atkinson (ORCID: https://orcid.org/0000-0001-5834-8315)
- Lukas Fenner (ORCID: https://orcid.org/0000-0003-3309-4835)
- José María Miró (ORCID: https://orcid.org/0000-0001-8057-7755)
- Anastasia Antoniadou (ORCID: https://orcid.org/0000-0003-0991-9198)
- Hansjakob Furrer (ORCID: https://orcid.org/0000-0002-1375-3146)
- Alison D. Grant (ORCID: https://orcid.org/0000-0002-2437-5195)
- Matthias Egger (ORCID: https://orcid.org/0000-0001-7462-5132)
- Niels Obel (ORCID: https://orcid.org/0000-0002-5031-0045)
- Caroline Anne Sabin (ORCID: https://orcid.org/0000-0001-5173-2760)
- Cristina Mussini (ORCID: https://orcid.org/0000-0002-6615-4198)
- Marcel Zwahlen (ORCID: https://orcid.org/0000-0002-6772-6346)
- Laurence Meyer (ORCID: https://orcid.org/0000-0001-5707-2062)
- Daria Podlekareva (ORCID: https://orcid.org/0000-0003-3187-0597)
- Antonella Castagna
- Marc van der Valk (ORCID: https://orcid.org/0000-0002-8290-6425)
- Stéphane De Wit
- Philippe Morlat
- Rémonie Seng
Institutions
- University of Bern (CH)
- University of Modena and Reggio Emilia (IT)
- University of London (GB)
- Université Libre de Bruxelles (BE)
- Université de Bordeaux (FR)
- Vita-Salute San Raffaele University (IT)
- Inserm (FR)
- University of Cape Town (ZA)
- Université de Montpellier (FR)
- National and Kapodistrian University of Athens (GR)
- Washington University in St. Louis (US)
- Masaryk University (CZ)
- Université Paris-Saclay (FR)
- University Hospital of Bern (CH)
- Instituto de Salud Carlos III (ES)
- Bispebjerg Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Centre Hospitalier Universitaire de Bordeaux (FR)
- University of Bristol (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre de recherche en Epidémiologie et Santé des Populations (FR)
- Bordeaux Population Health (FR)
- Centro de Investigación Biomédica en Red (ES)
- Stichting HIV Monitoring (NL)
- Amsterdam Institute for Global Health and Development (NL)
- Africa Health Research Institute (ZA)
- IRCCS Ospedale San Raffaele (IT)
- Institute of Social and Preventive Medicine (CH)
- University General Hospital Attikon (GR)
- Amsterdam University Medical Centers (NL)
- Centre Hospitalier Universitaire de Saint-Pierre (BE)
- Institut Alfred Fournier (FR)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Centre of Excellence for Health, Immunity and Infections (DK)
- Bicêtre Hospital (FR)
- University College London (GB)
- Universitat de Barcelona (ES)
- University of Amsterdam (NL)
- University of KwaZulu-Natal (ZA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1371/journal.pone.0312035
- Citations
- 5
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- National Science Foundation
- Styrelsen för Internationellt Utvecklingssamarbete
- European Commission
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Augustinus Fonden
- National Institute of Allergy and Infectious Diseases