Determination of the mean duration of recent infection and false recency rate for the HIV triplex multiplex bead assay
The HIV Triplex assay demonstrates a longer dynamic range compared to current HIV recency assays with a low FRR for cutoffs examined. With a longer dynamic range and low FRR, the MDRI for recent infection can be extended as appropriate to detect more recent infections, increasing the value of incidence assays benefiting public health surveillance and future surveys.
Authors
- Amy Zheng (ORCID: https://orcid.org/0000-0003-3048-3667)
- Bharat Parekh (ORCID: https://orcid.org/0000-0002-1088-4263)
- Mervi Detorio (ORCID: https://orcid.org/0009-0000-8114-2112)
- Jeni Vuong (ORCID: https://orcid.org/0000-0002-2038-6356)
- Ernest L. Yufenyuy
- Robert A. Domaoal (ORCID: https://orcid.org/0000-0002-0629-9459)
Institutions
- Centers for Disease Control and Prevention (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1371/journal.pone.0311829
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. President’s Emergency Plan for AIDS Relief
- Centers for Disease Control and Prevention
- Agency for Toxic Substances and Disease Registry