Evaluation of general anesthesia protocols for a highly controlled cardiac ischemia-reperfusion model in mice
In this study, the combination alfaxalone/medetomidine/buprenorphine (80/0,3/0,075 mg.kg-1, s.c.) associated with reversal by atipamezole was a reliable anesthetic protocol for murine surgery, particularly for the study of ischemia-reperfusion.
Authors
- Juliette Geoffray (ORCID: https://orcid.org/0000-0001-6849-085X)
- Gabriel Bidaux (ORCID: https://orcid.org/0000-0002-6162-3223)
- Michel Ovize (ORCID: https://orcid.org/0000-0002-2146-9874)
- Ludovic Gomez (ORCID: https://orcid.org/0000-0001-8509-4955)
- Christelle Léon (ORCID: https://orcid.org/0000-0001-8229-5401)
- Lionel Augeul (ORCID: https://orcid.org/0000-0002-2832-8089)
- Bruno Pillot (ORCID: https://orcid.org/0000-0002-1499-3299)
- Catherine Vogt
- Pascal Chiari (ORCID: https://orcid.org/0000-0003-2003-936X)
- A Ruelle
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Inserm (FR)
- Hospices Civils de Lyon (FR)
- Laboratoire de recherche en cardiovasculaire, métabolisme, diabétologie et nutrition (FR)
- Hôpital Louis Pradel (FR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1371/journal.pone.0309799
- Citations
- 2
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.85