Potential of patchouli (Pogostemon cablin) and champaca (Magnolia champaca) oils incorporated in facial wash formulation for effective anti-aging on human skin

Context: The patchouli (Pogostemon cablin) and yellow champaca (Magnolia champaca) oils present a promising natural alternative compared to synthetic anti-aging products that may entail potential side effects in facial wash formulations. Aims: To assess the safety and effectiveness of the combination of P. cablin and M. champaca oils in a facial wash formulation for preventing and reducing skin aging. Methods: The antioxidant activity of P. cablin and M. champaca oil was assessed using DPPH, ABTS, and FRAP methods. The quality assessment of the facial wash included organoleptic, homogeneity, pH, viscosity, and foam height evaluations. Simultaneously, the stability test encompassed accelerated, prolonged, and centrifugation stability evaluations. The clinical testing of the formulation involved the assessment of elasticity, pigment, and moisture content. Results: The results revealed that the antioxidant tests conducted on P. cablin and M. champaca oil, utilizing DPPH, ABTS, and FRAP methods, produced values IC50 (μg/mL) of 61.77 and 81.05, 36.33 and 69.60, and 101.85 and 132.06, respectively. These findings suggest that P. cablin and M. champaca oil could be effectively incorporated into a facial wash, meeting favorable evaluation criteria. The formulated product exhibited antioxidant activity, effectively enhanced elasticity and moisture content, reduced facial pigmentation, displayed no signs of irritation, including erythema and edema, and complied with standards for microbial and heavy metal contamination parameters. Conclusions: The results affirm that P. cablin and M. champaca oil hold the potential to be developed as anti-aging agents in facial wash cosmetic products, as validated by clinical tests on human skin.