Interdigitated Electrodes (IDEs)-Supported Biosensing for Efficient Point-of-Care Applications

Developing efficient micro-/nano-enabled sensing platforms based on the 5th and 6th generation is an escalating field where the data can be collected, transferred, and analyzed using AI and IoT systems in point-of-care (POC) situations. For personalized health, detecting low-concentration biomarkers requires highly efficient sensing electrodes. Interdigitated electrodes (IDEs)-based biosensors show promise due to their integration with microelectronics and ability for health monitoring. Systematic exploration of innovative designs, fabrication techniques, and surface chemistry is key to overcoming challenges and enabling efficient biosensing. This article explores IDEs’ potential in the early detection of diseases like cancer, COVID-19, and diabetes and discusses future directions.