Polygenic risk, aspirin, and primary prevention of coronary artery disease

The balance between net benefit and harm on aspirin in the primary prevention setting shifts favourably in individuals with an elevated genetic predisposition.

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Publication Details

Journal
European Heart Journal - Cardiovascular Pharmacotherapy
Published
2024-10-25
DOI
https://doi.org/10.1093/ehjcvp/pvae085
Citations
7
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
4.01

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article

Polygenic risk, aspirin, and primary prevention of coronary artery disease

Paul Lacaze, Franz‐Josef Neumann, Amit Khera, Chenglong Yu et al.
7 citations
European Heart Journal - Cardiovascular Pharmacotherapy
Lipoproteins and Cardiovascular Health
4.01
article

Polygenic risk, aspirin, and primary prevention of coronary artery disease

Paul Lacaze, Franz‐Josef Neumann, Amit Khera, Chenglong Yu, Sophia Zoungas, Pradeep Natarajan, Stephen James Nicholls, John J. McNeil, Christopher M. Reid, Rory Wolfe, Aniruddh P. Patel, Harpreet Singh Bhatia, Sotirios Tsimikas, Andrew Tonkin
article en
7 citations

Abstract

The balance between net benefit and harm on aspirin in the primary prevention setting shifts favourably in individuals with an elevated genetic predisposition.

European Heart Journal - Cardiovascular PharmacotherapyVol. 11(1)
Broad Institute (US), Brigham and Women's Hospital (US), Harvard University (US), University of California San Diego (US), Massachusetts General Hospital (US), Verve Therapeutics (United States) (US), German Centre for Cardiovascular Research (DE), Australian Association of Gerontology (AU), Monash University (AU)
Commonwealth Scientific and Industrial Research Organisation, Monash University, Menzies Institute for Medical Research, National Institutes of Health, Medical Research Council, National Health and Medical Research Council, National Institute on Aging, National Heart, Lung, and Blood Institute, National Cancer Institute
Good health and well-being
Openalex Percentile: Top 6%
Lipoproteins and Cardiovascular Health
4.01
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