Comparative visual performance of ultraviolet light-filtering and violet light-filtering monofocal intraocular lenses of the same material and basic design

We compared the visual performance of ZCB00 ultraviolet light-filtering and ZCB00V violet light-filtering monofocal intraocular lenses (IOLs) (both Johnson & Johnson Surgical Vision) with the same materials and basic design in cataract patients treated from 2011 to 2020. The evaluations were performed 10 weeks after the last surgery for implantation of bilateral lenses ≤ 3 months apart. The ZCB00 and ZCB00V groups included 904 eyes from 452 patients (age 72.3 ± 6.8 y; women/men, 268/184) and 1374 eyes from 687 patients (age 73.0 ± 7.4 y; women/men, 415/272), respectively. Statistical validity was confirmed using a linear mixed-effects model with binocular data and adjustments for age, sex, subjective refraction cylinder, subjective refraction spherical equivalent, corneal astigmatism, axial length, pupil diameter, and corneal higher-order aberrations. ZCB00 showed slightly but significantly better results (p < 0.05, Wald) for uncorrected intermediate/near visual acuity, corrected near visual acuity, and components of the 25-item Visual Function Questionnaire (VFQ-25) (Role_Limitation, Mental_Health, Social_Function, Distance_Vision, Color_Vision). Additionally, ZCB00V showed significantly better contrast sensitivity with glare (visual angle of target: 6.3°/4.0°/0.7°; p < 0.00068, Wald); slightly but significantly better contrast sensitivity without glare (4.0°/2.5°/1.6°) and with glare (2.5°/1.6°/1.0°), VFQ-25 General_Health scores, and near spectacle independence; and slightly but significantly smaller higher-order aberrations (internal, scaled to a 6-mm pupil; Wavefront_6_post_I_Trefoil) (p < 0.05, Wald).