Association between accumulation of 2-hydroxyglutarate detected by MR spectroscopy and preoperative seizure in IDH-mutant glioma
An elevated 2HG concentration on MRS could be associated with preoperative seizure, suggesting that 2HG accumulation increases the risk of preoperative seizures in IDH-mutant gliomas.
Authors
- Takashi Sasayama (ORCID: https://orcid.org/0000-0002-5593-9045)
- Masato Komatsu (ORCID: https://orcid.org/0000-0003-2007-0252)
- Shunsuke Yamanishi (ORCID: https://orcid.org/0000-0002-8734-4169)
- Hiroaki Nagashima (ORCID: https://orcid.org/0000-0003-0685-7382)
- Hirofumi Iwahashi
- Yuichiro Somiya
- Ryohei Sasaki (ORCID: https://orcid.org/0000-0002-4994-9386)
- Mitsuru Hashiguchi (ORCID: https://orcid.org/0000-0003-2405-0400)
- Takiko Uno
- Tomoo Itoh (ORCID: https://orcid.org/0000-0003-1498-5018)
- Kazuhiro Tanaka
Institutions
- Kobe University Hospital (JP)
- Hyogo Prefectural Cancer Center (JP)
- Kobe University (JP)
Publication Details
- Journal
- Journal of neurosurgery
- Published
- 2024-10-01
- DOI
- https://doi.org/10.3171/2024.6.jns24166
- Citations
- 2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.88