Biomarkers of microbial translocation and generalized inflammation are associated with frailty among people with HIV
Higher levels of biomarkers linked to microbial translocation and systemic inflammation are associated with higher average frailty scores over time in a cohort of virally suppressed PWH, highlighting these pathways as potential interventional targets for mitigating frailty in PWH.
Authors
- Alan Landay (ORCID: https://orcid.org/0000-0001-9645-1356)
- Joseph A. Delaney (ORCID: https://orcid.org/0000-0003-1771-1776)
- Gabriele Beck‐Engeser
- Edward R. Cachay (ORCID: https://orcid.org/0000-0002-2452-7558)
- Lydia N. Drumright (ORCID: https://orcid.org/0000-0002-3361-8080)
- L. Sarah Mixson (ORCID: https://orcid.org/0009-0006-5149-8859)
- Amanda L. Willig (ORCID: https://orcid.org/0000-0001-8802-4311)
- Heidi M. Crane (ORCID: https://orcid.org/0000-0002-3308-7005)
- Andrew W. Hahn (ORCID: https://orcid.org/0000-0002-9552-1700)
- Michael S. Saag (ORCID: https://orcid.org/0000-0002-8866-1043)
- Sonia Napravnik (ORCID: https://orcid.org/0000-0002-9032-3713)
- Stephanie A. Ruderman (ORCID: https://orcid.org/0000-0002-0058-5729)
- Mari M. Kitahata (ORCID: https://orcid.org/0000-0002-5410-7175)
- Robin M. Nance (ORCID: https://orcid.org/0000-0002-4412-4844)
- Laura Bamford (ORCID: https://orcid.org/0009-0005-7192-6075)
- Bridget M. Whitney (ORCID: https://orcid.org/0000-0002-3738-5704)
- Gabrielle C. Ambayec
- Peter W. Hunt (ORCID: https://orcid.org/0000-0003-0967-3300)
Institutions
- University of North Carolina at Chapel Hill (US)
- University of California, San Francisco (US)
- University of Washington (US)
- University of Alabama at Birmingham (US)
- University of California San Diego (US)
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- AIDS
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1097/qad.0000000000004047
- Citations
- 3
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.07