Expanding the biosynthesis spectrum of hydroxy fatty acids: unleashing the potential of novel bacterial fatty acid hydratases
Our study demonstrates that fatty acid hydratases can be classified into three subtypes based on their regioselectivity and provides insights into their preferred substrate structures. These understandings pave ways for the design of optimal fatty acid hydratase variants and bioprocesses for the cost-efficient biosynthesis of hydroxy fatty acids.
Authors
- Garrett Wong (ORCID: https://orcid.org/0000-0001-5115-7743)
- Yu Chyuan Heng (ORCID: https://orcid.org/0000-0001-9754-5258)
- Sandra Kittelmann (ORCID: https://orcid.org/0000-0002-6019-9854)
Institutions
- National University of Singapore (SG)
- Wilmar International (Singapore) (SG)
Publication Details
- Journal
- Biotechnology for Biofuels and Bioproducts
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1186/s13068-024-02578-2
- Citations
- 4
- Primary Topic
- Enzyme Catalysis and Immobilization
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National University of Singapore