Clinical Relevance of Specific IgE in Penicillin Allergy Investigation

A history of an immediate type reaction requiring treatment, combined with elevated specific IgE to one or more penicillins is suggestive of an IgE mediated penicillin allergy and further allergy investigations may not be needed. Specific IgE to penicillins may be used early in allergy investigation of patients with severe immediate type reactions to penicillins.

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Publication Details

Journal
International Archives of Allergy and Immunology
Published
2024-10-25
DOI
https://doi.org/10.1159/000541243
Citations
2
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
0.90
Controls
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article

Clinical Relevance of Specific IgE in Penicillin Allergy Investigation

Lars K. Poulsen, Lars Blom, Holger Mosbech, Jonas Bredtoft Boel et al.
2 citations
International Archives of Allergy and Immunology
Drug-Induced Adverse Reactions
0.90
article

Clinical Relevance of Specific IgE in Penicillin Allergy Investigation

Lars K. Poulsen, Lars Blom, Holger Mosbech, Jonas Bredtoft Boel, Sara Fransson, Lene H. Garvey, Victor Lendal, Natasha Kahlhofen
article en
2 citations

Abstract

A history of an immediate type reaction requiring treatment, combined with elevated specific IgE to one or more penicillins is suggestive of an IgE mediated penicillin allergy and further allergy investigations may not be needed. Specific IgE to penicillins may be used early in allergy investigation of patients with severe immediate type reactions to penicillins.

International Archives of Allergy and ImmunologyVol. 186(4)
University of Copenhagen (DK), Gentofte Hospital (DK)
Openalex Percentile: Top 23%
Drug-Induced Adverse Reactions
0.90
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