Basophils: Regulators of lung inflammation over space and time
In this issue of JEM, Schuijs et al. (https://doi.org/10.1084/jem.20240103) highlight a novel role for basophils during allergic immune responses to house dust mites (HDM). They reveal that interleukin-33 (IL-33)-activated basophils facilitate the recruitment and extravasation of Th2 cells into the lungs during a specific time frame via their interactions with pulmonary endothelial cells.
Authors
- Clare M. Lloyd (ORCID: https://orcid.org/0000-0001-8977-6726)
- Régis Joulia (ORCID: https://orcid.org/0000-0002-7908-5670)
Institutions
- Lung Institute (US)
- Imperial College London (GB)
Publication Details
- Journal
- The Journal of Experimental Medicine
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1084/jem.20241663
- Citations
- 1
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.24
Funders
- Fondation Acteria
- Wellcome Trust
- European Federation of Immunological Societies