Poliumoside inhibits apoptosis, oxidative stress and neuro-inflammation to prevent intracerebroventricular streptozotocin-induced cognitive dysfunction in Sprague–Dawley rats: an in vivo, in vitro and in silico study
This study has demonstrated that PMD has a significant impact on AD by inhibiting ACheE and restoring neurotransmitter levels, which enhances Ach levels in rats, and improves cognitive impairment in STZ rats.
Authors
- Guocheng Liu (ORCID: https://orcid.org/0000-0001-8897-2338)
- Bineng Chen
- Ya-Nan Zuo
- Xiaokun Li (ORCID: https://orcid.org/0000-0002-6645-6890)
Institutions
- Fujian Medical University (CN)
- Liuzhou Maternal and Child Health Hospital (CN)
- Liuzhou General Hospital (CN)
- Zhangzhou Municipal Hospital of Fujian Province (CN)
- The 180th Hospital of PLA (CN)
- Northern Jiangsu People's Hospital (CN)
Publication Details
- Journal
- Folia Morphologica
- Published
- 2024-11-13
- DOI
- https://doi.org/10.5603/fm.101463
- Citations
- 7
- Primary Topic
- Advanced Nanomaterials in Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.82