Sopravvivenza a lungo termine in paziente affetta da carcinoma della mammella metastatico trattata con sacituzumab govitecan
The clinical case presented refers to a woman suffering from metastatic breast cancer treated with sacituzumab govitecan (SG) who has a long progression-free survival. The case is characterized by the extreme aggressiveness of the neoplastic disease that relapses during adjuvant hormonal treatment with a metastatic disease that presents immunohistochemical characteristics different from the primary tumor. After first-line therapy with nabpaclitaxel and atezolizumab and the subsequent one with carboplatin and gemcitabine, both characterized by short PFS, the third line with SG is characterized by obtaining a complete response and a prolonged PFS as well as extreme tolerability that continues to this day after 15 months of treatment.
Authors
- Luigi Mascia
- Carlo Mulas
Institutions
- Azienda Ospedaliera G. Brotzu (IT)
Publication Details
- Journal
- Recenti Progressi in Medicina
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1701/4357.43484
- Primary Topic
- Cancer Treatment and Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 0.00