Sopravvivenza a lungo termine in paziente affetta da carcinoma della mammella metastatico trattata con sacituzumab govitecan

The clinical case presented refers to a woman suffering from metastatic breast cancer treated with sacituzumab govitecan (SG) who has a long progression-free survival. The case is characterized by the extreme aggressiveness of the neoplastic disease that relapses during adjuvant hormonal treatment with a metastatic disease that presents immunohistochemical characteristics different from the primary tumor. After first-line therapy with nabpaclitaxel and atezolizumab and the subsequent one with carboplatin and gemcitabine, both characterized by short PFS, the third line with SG is characterized by obtaining a complete response and a prolonged PFS as well as extreme tolerability that continues to this day after 15 months of treatment.

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Publication Details

Journal
Recenti Progressi in Medicina
Published
2024-10-01
DOI
https://doi.org/10.1701/4357.43484
Primary Topic
Cancer Treatment and Pharmacology
Type
article
Field-Weighted Citation Impact
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article

Sopravvivenza a lungo termine in paziente affetta da carcinoma della mammella metastatico trattata con sacituzumab govitecan

Luigi Mascia, Carlo Mulas
Recenti Progressi in Medicina
Cancer Treatment and Pharmacology
article

Sopravvivenza a lungo termine in paziente affetta da carcinoma della mammella metastatico trattata con sacituzumab govitecan

Luigi Mascia, Carlo Mulas
article en

Abstract

The clinical case presented refers to a woman suffering from metastatic breast cancer treated with sacituzumab govitecan (SG) who has a long progression-free survival. The case is characterized by the extreme aggressiveness of the neoplastic disease that relapses during adjuvant hormonal treatment with a metastatic disease that presents immunohistochemical characteristics different from the primary tumor. After first-line therapy with nabpaclitaxel and atezolizumab and the subsequent one with carboplatin and gemcitabine, both characterized by short PFS, the third line with SG is characterized by obtaining a complete response and a prolonged PFS as well as extreme tolerability that continues to this day after 15 months of treatment.

Recenti Progressi in MedicinaVol. 115(10)
Azienda Ospedaliera G. Brotzu (IT)
Openalex Percentile: Top 67%
Cancer Treatment and Pharmacology
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