NRF3 suppresses the malignant progression of TNBC by promoting M1 polarization of macrophages via ROS/HMGB1 axis

NRF3 promotes M1 macrophage polarization through the ROS/HMGB1 axis, thereby inhibiting the malignant progression of TNBC. It is expected to become a therapeutic biomarker for TNBC.

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Publication Details

Journal
Cancer Biology & Therapy
Published
2024-10-23
DOI
https://doi.org/10.1080/15384047.2024.2416221
Citations
7
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
1.68

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article

NRF3 suppresses the malignant progression of TNBC by promoting M1 polarization of macrophages via ROS/HMGB1 axis

Mingming Quan, Ping Xing, Bangyi Lin, Zhenzhen Chen et al.
7 citations
Cancer Biology & Therapy
Immune cells in cancer
1.68
article

NRF3 suppresses the malignant progression of TNBC by promoting M1 polarization of macrophages via ROS/HMGB1 axis

Mingming Quan, Ping Xing, Bangyi Lin, Zhenzhen Chen, Wenbo Zhu
article en
7 citations

Abstract

NRF3 promotes M1 macrophage polarization through the ROS/HMGB1 axis, thereby inhibiting the malignant progression of TNBC. It is expected to become a therapeutic biomarker for TNBC.

Cancer Biology & TherapyVol. 25(1)
Wenzhou Medical University (CN), Taizhou Central Hospital (CN), Zhejiang Taizhou Hospital (CN), Taizhou University (CN)
Taizhou Municipal Science and Technology Bureau
Zero hunger
Openalex Percentile: Top 15%
Immune cells in cancer
1.68
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