Neoadjuvant combination immunotherapy in MSI/dMMR colorectal cancer

Neoadjuvant immune checkpoint inhibition (ICI) is a new approach to treat patients with colorectal cancer (CRC). The effects of combined neoadjuvant ICI in locally advanced, DNA mismatch repair (dMMR)-deficient/microsatellite instable (MSI) CRC were recently reported by de Gooyer et al. from the NICHE-3 trial. Further studies will determine whether these impressive pathological responses lead to long-term clinical benefit.

Authors

Institutions

Publication Details

Journal
Trends in cancer
Published
2024-10-24
DOI
https://doi.org/10.1016/j.trecan.2024.10.006
Citations
3
Primary Topic
Colorectal Cancer Treatments and Studies
Type
article
Field-Weighted Citation Impact
0.85

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Neoadjuvant combination immunotherapy in MSI/dMMR colorectal cancer

Meggy Suarez‐Carmona, Niels Halama
3 citations
Trends in cancer
Colorectal Cancer Treatments and Studies
0.85
article

Neoadjuvant combination immunotherapy in MSI/dMMR colorectal cancer

Meggy Suarez‐Carmona, Niels Halama
article en
3 citations

Abstract

Neoadjuvant immune checkpoint inhibition (ICI) is a new approach to treat patients with colorectal cancer (CRC). The effects of combined neoadjuvant ICI in locally advanced, DNA mismatch repair (dMMR)-deficient/microsatellite instable (MSI) CRC were recently reported by de Gooyer et al. from the NICHE-3 trial. Further studies will determine whether these impressive pathological responses lead to long-term clinical benefit.

Trends in cancerVol. 10(12)
German Cancer Research Center (DE), Johannes Gutenberg University Mainz (DE), Heidelberg University (DE), University Hospital Heidelberg (DE), University Medical Center of the Johannes Gutenberg University Mainz (DE)
Deutsches Krebsforschungszentrum
Good health and well-being
Openalex Percentile: Top 22%
Colorectal Cancer Treatments and Studies
0.85
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Neoadjuvant combination immunotherapy in MSI/dMMR colorectal cancer — Meggy Suarez‐Carmona, Niels Halama · Trends in cancer (2024) | TGRS Research Map | TGRS