Elevated Circulating Sclerostin Levels in Frail Older Adults: Implications beyond Bone Health
These findings, which for the first time explore the association between circulating sclerostin levels and frailty, have significant clinical implications, positioning sclerostin as one of potential blood-based biomarkers for frailty that captures the comprehensive physical, mental, and social aspects of the elderly, extending beyond its traditional role in bone metabolism.
Authors
- Seong Hee Ahn (ORCID: https://orcid.org/0000-0003-2558-2118)
- Seongbin Hong (ORCID: https://orcid.org/0000-0002-8189-395X)
- Yunju Jo (ORCID: https://orcid.org/0000-0002-6305-3324)
- Hee‐Won Jung (ORCID: https://orcid.org/0000-0002-2583-3354)
- Il‐Young Jang (ORCID: https://orcid.org/0000-0003-3617-3301)
- Eunhye Ji (ORCID: https://orcid.org/0000-0002-6274-8730)
- Dongryeol Ryu (ORCID: https://orcid.org/0000-0001-5905-6760)
- Eun‐Ju Lee (ORCID: https://orcid.org/0000-0003-4612-0625)
- Beom‐Jun Kim (ORCID: https://orcid.org/0000-0001-8591-1759)
- So Jeong Park
- Ji Yeon Baek (ORCID: https://orcid.org/0000-0001-7547-8015)
Institutions
- Ulsan College (KR)
- Asan Medical Center (KR)
- Gwangju Institute of Science and Technology (KR)
- University of Ulsan (KR)
- Inha University Hospital (KR)
Publication Details
- Journal
- Endocrinology and Metabolism
- Published
- 2024-10-24
- DOI
- https://doi.org/10.3803/enm.2024.2100
- Citations
- 1
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.33
Funders
- Ministry of Health and Welfare
- Korea Health Industry Development Institute
- Asan Institute for Life Sciences, Asan Medical Center