Multistage carcinogenesis in occupational cholangiocarcinoma: the impact of clonal expansion and risk estimation
Three-stage ICC carcinogenesis has been proposed. The high mutation burden levels caused by occupational exposure led to an immediate incidence of cancer. After a long period of relatively low cancer risk, an increased risk in older adults was also predicted.
Authors
- Katsuya Tsuchihara (ORCID: https://orcid.org/0000-0001-7507-2349)
- Sachiyo Mimaki
- Hiroshi Haeno (ORCID: https://orcid.org/0000-0002-6211-0649)
- Masahiko Watanabe (ORCID: https://orcid.org/0000-0002-5262-6799)
Institutions
- Shujitsu University (JP)
- Tokyo University of Science (JP)
Publication Details
- Journal
- Genes and Environment
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1186/s41021-024-00315-7
- Citations
- 1
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.57