Mechanism of minocycline activating Nrf2/Hmox1 pathway to prevent ferroptosis and alleviate acute compartment syndrome
Minocycline hinders ferroptosis via stimulating the Nrf2/Hmox1 pathway, which slows down the advancement of acute compartment syndrome.
Authors
- Ling He (ORCID: https://orcid.org/0000-0003-2702-2579)
- Zhao Huang (ORCID: https://orcid.org/0000-0002-2546-7104)
- Wencai Li (ORCID: https://orcid.org/0000-0002-5185-6218)
- Junjie Liu (ORCID: https://orcid.org/0000-0002-8982-107X)
- Yonghui Lao
- Xiong Liao
- Wei Su (ORCID: https://orcid.org/0000-0002-7672-1256)
Institutions
- Changsha Central Hospital (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- University of South China (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1186/s13018-024-05183-z
- Citations
- 1
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- Guangxi Medical University