Immunomodulatory properties of extracellular vesicles isolated from bone marrow of patients with neuroblastoma: role of PD-L1 and HLA-G
We described the presence of HLA-G and PDL1-bearing EVs in the BM of NB patients, which may represent a mechanism performed by resident BM cells to counteract the inflammation occurring in the BM microenvironment of NB patients.
Authors
- Roberto Gramignoli (ORCID: https://orcid.org/0000-0003-3362-4170)
- Fabio Morandi (ORCID: https://orcid.org/0000-0002-2849-7595)
- Danilo Marimpietri (ORCID: https://orcid.org/0000-0001-6360-1661)
- Maria Valeria Corrias (ORCID: https://orcid.org/0000-0002-7316-0772)
- Gino Tripodi (ORCID: https://orcid.org/0000-0002-3259-4718)
- Irma Airoldi (ORCID: https://orcid.org/0000-0002-4352-8396)
Institutions
- Istituto Giannina Gaslini (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-24
- DOI
- https://doi.org/10.3389/fimmu.2024.1469771
- Citations
- 5
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.17